Glaucoma (Mondays at AM and Tuesdays at AM)
Glaucoma specialists provide comprehensive glaucoma care with the latest treatments and surgical procedures for all types of glaucoma.
We diagnose glaucoma using the latest equipment, including optical coherence tomography (OCT), OCT angiography, anterior segment OCT, and various types of visual field testing. We provide patients the best medical and surgical care with the highest degree of respect and empathy. For surgical treatment, we perform laser surgery, traditional glaucoma surgeries such as trabeculotomy and trabeculectomy, tube-shunt surgery, and the latest minimally invasive glaucoma surgery. We also provide high education and training for eye professionals and strive to improve the quality of life of all patients through basic and clinical researches on glaucoma.
Neuro-ophthalmology (Mondays at PM)
The Neuro-ophthalmology clinic specializes in visual disorders related to the central nervous system. We provide cutting-edge clinical care to a wide range of diseases, including visual pathways from the optic nerve to the brain, ocular motility dysfunction, or pupillary abnormalities.
In addition to medical care, we are also conducting many research activities. As the latest research, we are working on specified clinical research, using skin electrical stimulation for Leber hereditary optic neuropathy. As for basic research, we investigate pathophysiological analysis of Leber hereditary optic neuropathy using patient-derived induced pluripotent stem cells. We are actively engaged in both clinical care and research related to neuro-ophthalmology.
Strabismus and Amblyopia (Tuesdays at PM)
We provide diagnostic and comprehensive evaluation and treatment for children with eye and visual problems including strabismus, amblyopia, congenital anomalies of the eyes, cataracts, glaucoma etc. Expert pediatric ophthalmologists perform delicate surgical procedures to treat strabismus, and pediatric eye diseases.
Retina and Vitreous (Monday PM, Wednesday AM・PM, Thursday AM)
The team in this service is providing appropriate treatment to patients with various diseases.
Anti-vascular endothelial growth factor (VEGF) therapy based on OCT imaging has been a mainstay for the management of macular edema secondary to diabetic retinopathy (DR) or retinal vein occlusion, which is the representative cause of vision loss in retinal disease. In addition, we also offer the combination therapy of anti-VEGF injection with laser photocoagulation, steroid therapy, or surgery (vitrectomy), given the individual situation in each patient.
Neovascular age-related macular degeneration (AMD) and central serous chorioretinopathy (CSC) are well-known macular diseases, which can finally lead to central vision loss. We treat neovascular AMD with not only continuous anti-VEGF monotherapy but also the combination therapy of photodynamic therapy (PDT) and anti-VEGF injection based on disease activity, which can reduce the number of treatments. We also offer reduced PDT therapy to the patient with CSC which is approved by the institutional review board of Kobe University Hospital. These advanced therapies have shown desirable results.
In vitreoretinal surgical management, highly-skill and experienced surgeons performs 27-G vitrectomy utilizing both 3D visualization system and intraoperative optical coherence tomography. The surgery using these cutting-edge devices confer benefits on the patients who need vitrectomy. Recently, we developed intraoperative 3D fluorescein angiography-guided vitrectomy and the novel technique of cystotomy with fibrinogen clot removal for refractory macular edema.
We are also focusing on the management of pediatric vitreoretinal diseases, including retinopathy of prematurity (ROP). We evaluate fundus status using a specific camera for neonatal and pediatric imaging to judge the correct timing of appropriate treatment. For the infant who has advanced ROP, we can give anti-VEGF therapy, laser treatment, and vitrectomy.
Our clinic is involved in several international clinical trials assessing new therapies for AMD and DR and plays an important role as a tertiary referral center.
Uveitis (Thursdays at PM)
In Uveitis clinic, we have a dedicated service to maintain quality of vision over a long period. The physicians in this service are providing professional medical care for the management of the patients utilizing multimodal imaging with advanced devices (e.g., wide-angle fundus photo and fluorescence angiography, SD-OCT, SS-OCT angiography, etc.) as well as detailed clinical examinations and medical interviews. However, in clinical practice, the cause of uveitis is unidentified in approximately 1/3 of cases, which often gives patients a sense of uneasiness. To overcome this problem, we constructed a system by which we can provide such patients with an optimal treatment based on acquired information. In cases with unclassified uveitis and severe vitreous opacification, we do not hesitate to perform vitreous surgery to improve vision as well as to narrow down the causes of uveitis.
Regarding the treatment of uveitis, we offer state-of-art treatment such as vitrectomy for sarcoidosis with macular lesion, infliximab and cyclosporine combination therapy for Behçet’s uveoretinitis, and adalimumab therapy for refractory noninfectious uveitis. We also employ multidisciplinary therapy unique to university hospital (e.g., systemic chemotherapy + radiation therapy + intraocular methotrexate injections for vitreoretinal lymphoma). In addition, we developed a novel filtering surgery (Tenon’s retractor-assisted trabeculectomy) and use it as a remedy for elevated intraocular pressure in patients suffering from uveitic glaucoma .
Cornea and Dry Eye (Fridays at AM)
In Cornea and Dry Eye clinic, we treat a variety of corneal diseases including corneal infection, immune disorders, keratoconus, corneal dystrophies, trauma, bullous keratopathy, dry eye, and allergic diseases.
We perform corneal surgeries, including corneal transplantation such as penetrating keratoplasty (PKP) and Descemet's stripping automated endothelial keratoplasty (DSAEK), and amniotic membrane transplantation.
Orbita (Fridays at PM)
In Orbita clinic, we treat thyroid-associated ophthalmopathy, orbital tumors, eyelid tumors, and disorders of the lacrimal system apparatus.